研究目的：膀胱結石傳統上多以開刀取石術或經尿道膀胱碎石術來治療，而大於三公分的膀胱結石我們試圖利用經皮恥骨上膀胱造廔碎石的方式將結石取出。材料與方法：我們有六位男性病患在經皮恥骨上膀胱造廔口利用氣動式碎石棒經由零度26Fr.腎臟鏡治療（平均結石大小為5.4公分），然後利用石頭鉗將碎石夾出及膀胱鏡沖洗出來。所得結果並與二十一位接受經尿道膀胱碎石術（平均結石大小為2.4公分）及六位接受開刀取石術（平均結石大小為5.8公分）相比較。結果：結石有效清除率在經皮恥骨上膀胱造廔碎石術為0.11公分/分鐘，經尿道膀胱碎石術為0.06公分/分鐘，開刀取石術為0.09公分/分鐘.住院天數經皮恥骨上膀胱造廔碎石術為3.3天，經尿道膀胱碎石術為2.4天，開刀取石術為6.5天。結論：對於3公分以上大的膀胱結石而言經皮恥骨上膀胱造廔碎石術是一項安全且有效的術式。

OBJECTIVE: Bladder stone is traditionally treated with transurethral cystolithotripsy or open cystolithotomy. In this study, percutaneous suprapubic cystolithotripsy was attempted to deal with bladder stones larger than 3 cm in diameter. PATIENTS AND METHODS: Six male patients were treated with percutaneous suprapubic cystolithotripsy for large bladder stones(stone burden average 5.4cm). These stones were effectively disintegrated with Pneumatic Swiss Lithoclast via a 26Fr. zero degree nephroscope placed through the suprapubic cystostomy tract. The fragmented stones were removed by forceps via the suprapubic tract and cystoscopic irrigation. We compared this method with transurethral cystolithotripsy (n=21, stone burden average 2.5cm) and open cystolithotomy (n=6,stone burden average 5.8cm). RESULTS: The efficacy index of stone removal was 0.11 cm/min for percutaneous suprapubic cystolithotripsy, 0.06 cm/min for transurethral cystolithotripsy and 0.09 cm/min for open cystolithotomy. The hospital stay was 3.3 days for percutaneous suprapubic cystolithotripsy, 2.4 days for transurethral cystolithotripsy and 6.5 days for open cystolithotomy. CONCLUSIONS: Percutaneous suprapubic cystolithotripsy is a safe and effective alternative technique for the removal of large bladder stones.