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中華民國泌尿科醫學會雜誌

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篇名 Incidental Renal Cell Carcinoma:Experience at National Cheng Kung University Hospital
卷期 12:4
並列篇名 偶發性腎臟細胞癌:成大經驗
作者 林憲雄蔡宗欣林信男唐一清楊文宏張建成鄭鴻琳林永明蔡育賢
頁次 166-169
關鍵字 腎細胞癌偶發性發現renal cell carcinomaincidental findingTSCI
出刊日期 200112

中文摘要

研究目的: 由於超音波及電腦斷層的盛行,偶發性腎臟腫瘤逐漸增加。為了評估偶發性腎臟細胞癌的特徵,我們回顧92位經病理證實腎臟細胞癌患者進行分析。材料與方法: 從1988年6月至2001年1月,在成大醫院我們回顧902位經病理證實腎臟細胞癌患者。根據病歷紀綠病患的症狀,使用的影像工具,腫瘤分期,腫瘤大小,復發情況及預後進行分析。結果: 在92位病人中,有61位男性,31位女性,男女比率為1.97。病患年齡從19到87歲,平均57.8歲。六十三位病人(68.5%)呈現與腎臟相關的症狀。二十九位病人(31.5%)為健康檢查或因非腎臟相關症狀而意外發現。有72.4%的偶發性腎細胞癌屬侷限於器官的疾病,相較於有症狀的腎臟瘤占30.1%。偶發性腎腫瘤比有症狀的腎腫瘤小。無症狀之患者比有症狀的患者有較好的五年存活率(92.3%比52.2%)。術後局部復發或遠處轉移情形,偶發性腎腫瘤比有症狀的腎腫瘤低(6.9%比30.2%)。結論: 由於非侵犯性影像工具的盛行,使能早期診斷早期治療腎腫瘤,並取得較好的結果。

英文摘要

OBJECTIVES: As ultrasonography and computed tomography have become commonplace, renal rumors are increasingly being detected incidentally. To assess the characteristics of incidentally discovered renal cell carcinoma, we retrospectively reviewed 92 cases of pathologically proven disease. MATERIALS AND METHODS: From June1998 to January 2001, totally 90 cases of pathologically proven renal cell carcinoma (RCC) were reviewed at NCKUH. Charts were analyzed to record the presenting symptoms, image modality used, tumor stage, tumor size, local tumor recurrence or distant metastasis, and outcome. RESULTS: Of the 92 patients, there were 61 males and 1 females with a male to female ratio of 1.97. Patients’ ages ranged from 19 to 87 with a mean of 57.8 years. Sixty-three patients (68.5%) presented with clinical symptoms and/or signs related to renal pathology. Twenty-nine patients (31.5%) were incidentally diagnosed during image studies for non-renal symptoms or routine health examinations. The overall detection of organ-confined disease (stages I and II) was 72.4% of the ”incidental” and 30.1% of the “symptomatic” group. Smaller tumor size was also found in the “incidental” group (5.17 vs. 8.72 cm). The overall 5-year survival rate for patients with incidentally detected RCC was 92.3%, and was 52.5% in those with symptomatic tumors. Postoperatively, there was local tumor recurrence or distal metastasis in 6.9% of patients with incidental RCC and 30.2% of symptomatic patients. CONCLUSIONS: With the widespread use of non-invasive image modalities, the detection of smaller, lower-stage renal tumors will significantly improve the outcome of this disease.

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