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中華民國泌尿科醫學會雜誌

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篇名 Early Experience with High Intensity Focused Ultrasound for the Treatment of Benign Prostate Hyperplasia
卷期 10:4
並列篇名 高能量聚焦超音波治療良性攝護腺肥大的早期經驗
作者 孫建偉賴明坤劉詩彬林祥明
頁次 149-154
關鍵字 高能量聚焦超音波良性攝護腺肥大high-intensity focused ultrasound benigh prostatic hyperplasiaTSCI
出刊日期 199912

中文摘要

高能量聚焦超音波(HIFU)能將超音波能量由治療探頭集中釋放於一指定點,在不產生中間組織的傷害及變化的情況下,治療區的溫度可高達攝氏80-100度,導致焦點區內出現缺血性壞死。西園醫院自1999年3月11日至5月17日止,以Sonablate-200治療22位前列腺肥大之病患,其平均年齡為65.63歲(60-83歲),以國際攝護腺症狀指數(IPSS),最高尿流速(Qmax),及生活品質指數(QOL)評估術前及術後(30天,90天)之變化。我們發現術後90天時,IPSS由22.77降至9.41,QOL由5.68降至3.41,Qmax由9.48升高至14.9ml/sec(p<0.0001).在我們早期的經驗認為,此種新能量治療良性前列腺肥大是一種安全有效且無重大術後併發症的療法。但儀器本身之改良及慎選病患也是必需的。

英文摘要

High-intensity focused ultrasound (HIFU) delivers ultrasonic energy to a local point at a distance from the ultrasonic transducer without injuring the tissue between transducer and local point. From March 11 to May 17 1999, we treated 22 patients (mean age 65.63 years, range 60 to 83) with symptomatic benigh prostatic hyperplasia(BPH) using the Sonablate-200 device. Preoperative and postoperative evaluations were made in 30 and 90 days using the International Prostate Symptom Score(IPSS), peak flow rate (Qmax) and a quality-of –life (QOL) score. The postoperative results in three months showed, in average, statistically significant improvement for IPSS(22.77 to9.41), QOL(5.68 to 3.41), and Qmax(9.48 ml/sec to 14.9ml/sec[p<0.0001]). There were no major complications. Our initial data demonstrate that this new technique is safe and effective for the treatment of BPH. (J Urol R.O.C.,10:149-154,1999)

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