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中華民國泌尿科醫學會雜誌

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篇名 Is the International Prostatic Symptom Score Higher in Elderly Males Treated for Chronic Airflow Obstruction
卷期 8:1
並列篇名 在治療中的慢性呼吸道阻塞症老年男性其國際攝護腺症狀指數是否較高?
作者 甘宗翔吳宏豪連德正陳光國張心湜
頁次 28-32
關鍵字 氣喘膀胱出口阻塞氣管擴張劑慢性阻塞性肺部疾病攝護腺asthmabladder outlet obstructionbronchodilatorschronic obstructive pulmonary disease prostateTSCI
出刊日期 199703

中文摘要

國際攝護腺症狀指數是目前最廣泛使用於評估良性攝護腺增生症患者症狀嚴重程度的指標。此問卷包括三個刺激性的症狀(頻尿、急尿、夜尿)及四個阻塞性的症狀(餘尿感、中斷性排尿、尿徑變細和等尿感)。在日常的觀察中,我們發現包括慢性阻塞性肺部疾病和氣喘等慢性呼吸道阻塞症的患者常常也深為攝護腺增生症的症狀所困擾。雖然以往偶而有些報告顯示,某些用於治療慢性氣道阻塞症的藥物會引起泌尿系統方面的症狀,然而並沒有研究確實比較使用藥物中的慢性呼吸道阻塞患者是否有較明顯的攝護腺症狀。在本實驗中,十七位藥物治療中的慢性氣道阻塞症老年男性及十八位非慢性呼吸道阻塞症老年男性在門診完成此問卷及其他的實驗室檢驗。經比較後發現:在年齡及其他的實驗室檢驗結果沒有明顯差異的情形下,兩組的刺激性症狀指數的差異有統計學上的意義。此結果我們推測應是治療慢性呼吸道阻塞藥物所導致,至於究竟是何種藥物的作用或是否有其他原因則有待日後更大規模的研究探討。

英文摘要

This study was conducted to compare the International Prostatic Symptom score (IPSS), including obstructive (symptom) score and irritative (symptom) score, between patients with chronic airflow obstruction (CAO) and those without CAO. Materials and Methods: Seventeen patients, aged 64 to 79 years (mean 71.4) with CAO under medical treatment for more than 2 years, participated in this study. Another 18 non-CAO men, aged 62 to 73 years (mean 68.6), were recruited as control. All of them were non-benign prostatic hyperplasia (BPH) or unrecognized BPH before. The IPSS was evaluated on an outpatient basis. Laboratory examinations including blood urea nitrogen (BUN), creatinine, prostate specific antigen (PSA) were collected, and the prostatic volume was measured with ultra-sonography. The difference in irritative (symptom) score was significant between CAO and non-CAO groups by Wilcoxon-Rank Sum W test. However, IPSS and obstructive (symptom) score showed no statistical difference between these 2 groups. Conclusion: In our study, elderly males with CAO under medical treatment seemed more likely to suffer from irritative symptoms of BPH.

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