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中華民國泌尿科醫學會雜誌

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篇名 Palliative Orthopedic Management for Bony Metastasis from Renal Cell Cabcinoma
卷期 6:1
並列篇名 腎細胞癌併骨轉移的骨科姑息療法
作者 高義盛陳光國陳天雄陳明村張心湜
頁次 19-23
關鍵字 腎細胞癌,,;,,骨轉移骨科療法renal cell carcinomabony metatasisorthopedic managementTSCI
出刊日期 199503

中文摘要

我們回溯了本院近十年來23個罹患腎細胞癌併骨轉移的病例,其中有8個病人因病理性骨折,1個因迫切性骨折而接受姑息性骨科手術。這9個病人中發生骨轉移的位置,有4個發生在股骨,3個發生在肱骨,2個在脊椎,9個病人中有6個是在骨科手術後才發現有腎細胞癌,有3個是在腎臟切除後才發生骨轉移。6個病人在手術後有明顯的疼痛緩解及功能性的改善。沒有因手術本身造成死亡的病例。至於存活率,有2個病人在手術後存活超過四個月而至今仍存活,2個病人在兩個月內死亡,4個病人存活超過四個月,而有1個病人失去追蹤。我們認為腎細胞癌併骨轉移引起病理性骨折,迫切性骨折或脊權之不穩定,未必是病危的徵兆,尤其是單一骨轉移的病灶,需要積極治療以改善病人生活品質。姑息性骨科手術可以減少病人的病痛並改善病人的生活品質。

英文摘要

A retrospective review of 23 cases of renal cell carcinoma (RCC) with bony metastasis was conducted in this hospital, covering the past 10 years when 9 patients had received palliative orthopedic management. Pathologiacl fracture had been diagnosed in eight patients and impending fracture in one. Four fractures had occurred at the femur, three at the humerus and two at the spine. Six of the nine patients were known to have RCC only after orthopedic procedure. Three cases developed bony metastasis after radical nephrectomy. Six of them had obvious functional improvement and pain relief, None died from the surgical procedure. Two patients are alive after the procedure but two patients survived less than two months. Four patients survived more than four months, and one was lost to follow-up. It was concluded that pathological fracture, impending fracture or spinal instability do not necessarily indicate a terminal event for patients with RCC and bony metastasis. On the other hand, palliatibve orthopedic procedures can decrease morbidity and improve the patient’s life quality.

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