我們所討論的這個病例，陰莖壞疽是由慢性腎衰竭導致繼發性副甲狀腺機能亢進所引發。為控制由感染所引發的癲癇發作（seizure），病人接受全陰莖切除術。我們在此回顧慢性腎衰竭所引發繼發性副甲狀腺機能亢進之代謝及血管變化，其能導致廣泛性缺血壞死及壞疽在尿毒症早期，預防高磷血症及低鈣血症，對於副甲狀腺機能亢進之治療是相當重要。次全副甲狀腺切除術只用於那些雖經內科藥物治療而血管及軟組織仍繼續鈣化的病例。

A case of penile gangrene caused by secondary hyperparathyoidism from chronic renal failure is presented. Total penectomy was used to control the septic condition. This case prompted a review of the literatures concerning secondary hyperparathyroidism in chronic renal failure which can lead to widespread ischemic necrosis and gangrene. In the early phase of uremia, careful monitoring of serum phosphate and calcium level may effectively prevent the development of secondary hyperparathyroidism. Once progressive calcification in the arterial wall and soft tissue has developed and the serum Ca × P product >75 mg/dl, subtotal parathyroidectomy is indicated.