本院在最近三年內，總共收集27例單純性腎囊腫接受由吸術合併囊腫內美樂黴素硬化治療，同時其術後臨床追蹤超過三個月的病例。在27例中總共治療36個腎囊腫，平均追蹤期為16.5個月。經治療後，21例（77.8%）自覺腰部不適之症狀隨即消失。三分之一（33.3%）的囊腫在治療後不再復發，而其它45.8%之囊腫則有超過一半以上的體積縮小。僅有1/5的病例治療無效，囊腫再度回復原來大小。在22例答覆問卷調查的病例中，14例（63.6%）對治療結果感到滿意，其它則無特別深刻的感受。全部27例病患均未發生治療合併症。我們認為，經超音波導引的抽吸術合併美樂黴素硬化治療，可考慮做為單純性腎囊腫的初步治療手段。

The effectiveness of cyst aspiration and adjuvant instillation of minocycline hydrochloride as a sclerosing agent for the treatment of simple renal cysts was evaluated in a total of 27 patients with 36 cysts. Twenty-one patients (77.8%) reported prompt relief of their flank discomfort immediately after treatment. In an average follow-up period of 16.5 months, 33.3% of the treated cysts had completely disappeared, while another 45.8% were at least 50% diminished in size when followed up by renosonography. Only one-fifth of the cysts were refractory to sclerotherapy, and remained stationary. No treatment associated complication nor malignant transformation was observed in the series, and 14 out of 22 (63.6%) who responded to our questionnaire claimed that their treatments satisfactory. It is suggested that cyst puncture and instillation of minocycline as the initial treatment modality for simple renal cysts because it is a simple, safe and relatively effective method.