篇名 | A Study of Renal Cell Carcinoma |
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卷期 | 2:3 |
並列篇名 | 腎細胞癌之研究 |
作者 | 丘祖毅 、 勞漢信 、 楊緒棣 、 蒲永孝 、 謝德生 、 陳淳 、 陳世乾 |
頁次 | 525-530 |
關鍵字 | renal cell carcinma 、 radical nephrectomy 、 simple nephrectomy 、 survival rate 、 TSCI |
出刊日期 | 199109 |
吾人收集從1977年至1990年,共94例曾在台大泌尿科接受手術的腎細胞癌病人。對於其臨床表現,性別及年齡層分佈,手術方法及追蹤結果作回溯性研究。符合臨床上所謂的三合症狀 (clinical ctiad),即腰痛,血尿及腰部腫塊僅佔人數的病人 (4.6%),然而只有其中一種表現者則為數不少,如血尿(30.0%)等。男性及女性病人各為64及30人,比例為2.1:1。大部份病人在51至60歲間發病,年齡從19歲至78歲不等。依疾病分期,第1期37人,第2期19人,第3A期25人,第3B期6人,第4期12人。94人當中,42位接受了根除性腎切除術,51例接受了單純性腎切除術,1位接受了部份腎切除術。第1.2期病人平均46.3個月會腫瘤再發,3A期及3B期分別為17.8及8.5個月,第1.2期及3期之病人5年存活率,接受根除性腎切除者為75.2%單純性腎切除術者為63.4%,而第4期病人僅有39.8%之5年存活率。
Ninety-four patients suffering from renal cell carcinoma and were admitted from 1977 to 1990 were analysed. The clinical manifestations, sex and age incidence, the method of surgical exploration and outcome were analysed. The clinical triad of pain, hematuria, and presence of a flank mass was found in relatively few patients (4.6%). However, patients were frequently encountered with one of these symptoms such as hematuria (30.0%). The male to female ratio was 2.1;1 (64:30). The majority of patients occurred in their 6 th decades (51 to 60 years) of life. The age ranged from 19 to 78. There were 37 stage I, 19 stage II, 25 stage IIIA, stage IIIB, and 12 stage IV patients. Among these patients, 42 underwent radical nephrectomies, 51 simple nephrectomies, and one partial nephrectomies, and one partial nephrectomy. Patients with stage I or II lesions had a mean interval to recurrence of 46.3 months, stage IIIA 17.8 months, and stage IIIB 8.5 months. The 5-year survival rates of simple and radical nephrectomy of stage I through stage III lesions were 63.4% and 75.2% respectively, while that of stage IV tumors underwent radical nephrectomies was 39.8%.