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中華民國泌尿科醫學會雜誌

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篇名 Normal Urinary Biochemistry of Chinese
卷期 1:4
並列篇名 正常中國人的尿中成份
作者 黃一勝穆瑞運楊啟瑞
頁次 269-275
關鍵字 supersaturationhyperuricosuriahypocitraturiametabolic evaluation of urolithiasisTSCI
出刊日期 199012

中文摘要

人類尿液中會影響尿路結石的成份有鈣,草酸,尿,檸檬酸,磷,鎂,鈉,酸鹼值及全尿量。目前之檢驗方法已能精確測出尿中之這些含量,只是尚無國人之正常值。本研究是把300位來本院做體檢的健康人士的尿液做上述各項成份之檢驗,易除曾患尿路結石、痛風、副甲狀腺機能亢進症、腸胃道手術或不正常之常規尿液檢查者皆不予統計後,有255例正常中國人(男性;170人,女性:85人)列為評估對象。統計結果:尿中鈣的濃度是168 ± 73毫克/天,草酸是 49.4 ± 17.6 毫克/天,磷 565 ± 213 毫克/天,尿酸 720 ± 255 毫克/天,檸檬酸 498 ± 216 毫克/天,鈉是 165 ± 63 毫克當量/天。尿液中較易引起結石的成份大多在男性比女性高,且是有意義的差別,諸如鈣、草酸、磷、尿酸,相反的,尿檸檬酸(尿石形成之抑制物)卻是女性比男性高。其他像酸鹼值、鈉,及全尿量則沒有性別差異。可能由於飲食習慣或種族之不同,國人之尿中成份濃度與外國之報告大有差異。要評估國人的尿石病人之致石危險因子為何,以中國人自己的正常值作為參考,將使診斷更為精確,治療效果更理想。

英文摘要

The risk factors of renal stone formation include the urinary calcium, oxalate, uricacid, citrate, pH, phosphorus, magnesium, sodium and total volume of urine, which either induce supersaturation or contribute to the inhibition of stone salts crystallizaion. In this study, 300 normal Chinese undergoing physical check-up at our hospital were studied. Two hundred and fifty-five persons (male : 170, female : 85) without urolithiasis, gout, hyper-parathyroidism, gastrointestinal surgery as well as abnormal urinalysis were evaluated. In normal Chinese, urinary calcium is 168 ± 73 mg/day, oxalate 49.4 ± 17.6 mg/day, phos-phorus 565 ± 213 mg/day, uric acid 720 ± 255 mg/day, citrate 498 ± 216 mg/day, sodium 165 ± 63 meq/day. Most urinary constituents which contribute to stone formation are sig-nificantly higher in male subjects, such as calcium(181 ± 75 vs 147 ± 71mg/day, p<0.05), oxalate (54.3 ± 15.7 vs 43.5 ± 18.1 mg/day, p<0.05),phosphorus (608 ± 206 vs 490 ± 204mg/day), uric acid (767 ± 269 vs 662 ± 228 mg/day, p<0.05). However, there are no sexual differences in urinary pH, sodium and total volume of urine. There are con-siderable differences in most variables of all urinary constituents between other reports and this study, possible due to dietary habit or racial factor. So, with reference to these data, the risk factors responsible for stone formation in Taiwan may be identified more precisely. (J Urol R.O.C., 1:269-275, 1990)

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