篇名 | 以大網膜包被靜脈植體修補狗之輸尿管缺損 |
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卷期 | 1:2 |
並列篇名 | Repair Ureteral Defect with Omentum Wrapped Vein Graft in Dongs |
作者 | 林登龍 、 陳明村 、 張延驊 、 李良明 、 張心湜 |
頁次 | 88-91 |
關鍵字 | ureteral defect 、 vein graft 、 omentum 、 TSCI |
出刊日期 | 199006 |
輸尿管常因外傷或手術誤傷而缺損一大段,治療上非常困難。如何修補長段輸尿管缺損,一直是亟待解決的問題。大網膜可以輸助供應血液,因此我們實驗研究以大網膜包被靜脈植體用來修補尿管缺損之可行性。共有六隻狗接受手術,以大網膜包被靜脈植體來修補人為的輸尿管缺損。只有三隻存活一年,其中二隻產生腎水腫。僅有一隻狗之輸尿管腔外觀正常,吻合處暢通。組織學檢查發現腎水腫者在植體處有嚴重之纖維化及炎性反應。而暢通之輸尿管則可見植體有骨化現象,移形上皮則由正常之輸尿管處延生蓋過骨化部分。此結果顯示大網膜包被靜脈植體修補輸尿管缺損之預後無法預測,仍無法於臨床運用。(J Urol R.O.C., 1: 88-91, 1990)
To repair Long ureteral defect is a difficult clinical problem. The present study investigated the feasibility of using omentum wrapped vein graft to repair long ureteral defect. Omentum Wrapped femoral vein graft was used to repair ureteral defect in 6 dogs. 3 dogs survived for one year. One of survived animals showed patent ureter without hydronephrosis. Histologic examination showed that the vein graft was replaced by a bone plate which was covered by transitional epithelium. The venous graft of the 2 other survived dogs was obliterated and the kidneys were hydronephrotic. Histological examination revealed severe inflammation and fibrosis of the graft. Because of inconsistent and unpredictable results in the experiment, we conclude that omentum wrapped vein graft is not a reliable material for repairing ureteral defect.