腎病症候群的患者易有併發血栓症的傾向，其中肺栓塞是最常引起死亡的併發症。我們報告一位22歲的男性病患，同時患有腎病症候群及肺栓塞，經過四週的抗凝及類固醇治療後，這位病患的腎功能改善，但肺栓塞仍存在且持續進展中，於抗凝劑由hcparin轉為coumadin時，病患突然死亡。

　　　　　Patients with nephrotic syndrome (NS) have an increased tendency to develop thromboembolism. Pulmonary embolism (PE) is the most common complication causing death in this event. We report a 22-year-old male who presented with NS, and was found to have massive PE. Anticoagulants and steroid were given to improve the clinical symptoms and signs of NS with PE. After treatment for more than 4 weeks, PE had persisted, although the patient's renal conditions improved. Finally, this patient expired abruptly when the anticoagulant was switching from heparin to coumadin.