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Annals of Nuclear Medicine and Molecular Imaging

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篇名 Assessment of Mediastinal Lymph Node Metastasis with [fee6]Tc-MIBI SPECT in Patients with Lung Cancer: Preliminary Results and Comparison with CT
卷期 12:3
並列篇名 鎝-99m-MIBI單光子射出斷層掃描於肺癌縱膈腔淋巴結轉移之評估:初步結果以及與電腦斷層的比較
作者 洪光威高嘉鴻王世楨
頁次 125-130
關鍵字 肺癌縱膈腔淋巴結鎝 99m MIBILung cancerMediastinal lymph node[fee6]Tc MIBI
出刊日期 199909

中文摘要

鎝-99m-MIBI單光子射出斷層掃描於肺癌縱膈腔淋巴結轉移之評估:初步結果以及與電腦斷層的比較前言:電腦斷層(CT)可用於精確的原發性肺癌定位,然而文獻報導高過40%的縱膈腔轉移無法以CT診斷。本研究評估以MlBI SPECT診斷肺癌病人縱膈腔轉移,並與電腦斷層作比較。
方法:本研究收集了9例肺癌患者,所有病人的術前分期的檢查都包括胸部電腦斷層和MlBI SPECT,並以術後病理報告作為評估縱膈腔轉移的依據。
結果:MIBI SPECT的敏感性為75%,特異性為80%,準確性為77.7%。CT的敏感性為25%,特異性為80%,準確性為67.7%。
結論:我們初步發現以MIBI SPECT評估我國肺癌病人縱膈腔轉移上,比電腦斷層有更高的敏感性及準確性。但仍需更廣泛的研究以進一步確認MIBI SPECT的臨床角色。

英文摘要

Backgrounds: Accurate imaging of primary lung cancer can be obtained with computed tomography (CT), by which up to 40% of mediastinal lymph node metastases reported were not visualized. The aim of this study was to assess the diagnostic contribution of M}BI SPECT vs. CT in the presurgical staging of lung cancer in Taiwan.
Methods: Nine patients with proved lung cancer were enrolled in the studs All the patients received computed tomography(CT) and 99m Tc MIBI SPECT of the thorax for presurgical stagin9. Postsurgical pathologic diagnosis was made and these patients were evaluated for the study of mediastinai lymph node involvement.
Results: The MIBI SPECT showed a diagnostic sensitivity of 75%, specificity of 80% and accuracy of 77.7%. CT gave a sensitivity of 25%, specificity of 80% and accuracy of 67.7%.
Conclusion: Through our study, we found that MIBI SPECT was more sensitive and accurate than CT in the assessment of mediastinal lymph nodes involvement for the patients in our country. However, more extensive studies weill be needed to further confirm the clinical role of MIBI SPECT.

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