姿態性頭痛可能是由自發性腦脊髓液溢漏所造成。溢漏的部位可能是單一的也可能是多發的。我們報告一個36歲懷疑有自發性顱內低壓症候群(spontaneous intracranial hypotension)的女性。她接受鎝－99m-DTPA腦池攝影(cistemography)。結果顯示腦脊髓液在上位及中間胸椎有滲漏情形且同位素在早期亦出現於病患雙側腎臟，確認了病患腦脊髓液溢漏的診斷。鎝－99m-DTPA腦池攝影在自發性顱內低壓症候群是一個有用的工具，可以用來診斷並確認脊髓液溢漏的部位。

Orthostatic headaches may be caused from spontaneous cerebrospinal fluid (CSF) leakage. The sites of spinal CSF leaks may be single or multiple. We presented a case of suspected spontaneous intracranial hypotension received 99mTc-DTPA radionuclide cisternography for further evaluation. The image findings are positive and provide an important clue to treat the patient. Radioisotope cisternography is a useful tool to diagnose and localize cerebrospinal fluid leakage in a case of intracranial hypotension syndrome.