鼻咽癌是一種上皮細胞癌,在中國南方、香港、新加坡和台灣的發生率較全球其他地區要來得高。影像醫學在臨床上對疾病的檢測、分期與治療非常重要。藉由電腦斷層影像與正子影像之融合將結構性資訊與功能性資訊做整合,氟-18-2-去氣葡萄糖正子斷層造影已成為對鼻咽癌之分期與再分期極為有用的工具,且可有效的降低偽陽性與偽陰性率。因此,本文認為氟-18-2-去氣葡萄糖正子電腦斷層造影很適合作為鼻咽癌分期與放射治療後腫瘤複發檢測的工具;此外,氟-18-2-去氣葡萄糖正子電腦斷層造影對已發現有頸部淋巴結轉移患者之未知原發腫瘤的定位亦極具效果。
Nasopharyngeal carcinoma (NPC) is an epithelial malignancy occurring worldwide, with particularly high frequencies in Southern China, Hong Kong, Singapore and Taiwan. Imaging is vital for detection, staging, and treatment. 2-[Fluorine-18] fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) has been shown to be a valuable imaging tool in patients for initial staging and restaging diagnosis of NPC. Dual-modality positron emission tomography/computed tomography (PET/CT) provides the technical basis for intrinsically aligned functional and morphologic data sets. The false-negative and false-positive rate may be decreased by using combined FDG-PET/CT. FDG-PET/CT may be as a standard clinical imaging modality in the staging of NPC and in the detection of recurrent disease after radiotherapy. It could provide valuable information in localizing primary tumor in patients with neck nodal metastases from an unknown primary tumor.