文章詳目資料

Annals of Nuclear Medicine and Molecular Imaging

  • 加入收藏
  • 下載文章
篇名 A Comprehensive Nuclear Imaging Approach to Predicting Patient Response to Cardiac Resynchronization Therapy – A Special Review Following the First Taiwan Nuclear Cardiology Symposium
卷期 23:3
並列篇名 核醫造影相位分析全方位預測心臟再同步治療效果
作者 陳季
頁次 143-152
關鍵字 heart failuregated SPECTmyocardial perfusion imagingcardiac resynchronization therapyphase analysis心衰竭心臟再同步治療心臟灌流影像單光子射出電腦斷層相位分析
出刊日期 201009

中文摘要

英文摘要

Heart failure affects more than 6 million people in the United States, and the number increases by more than 0.5 million every year. Acute decompensated heart failure accounts for over one million hospital admissions per year, and the estimated direct and indirect cost for heart failure in 2008 is more than $30 billion. Cardiac resynchronization therapy (CRT) has been approved by FDA as a treatment of heart failure patients refractory to conventional therapy. However, 20-40% of the patients who selected for CRT based on the conventional criteria do not respond to CRT. We developed a quantitative technique, phase analysis, which automatically measure left ventricular dyssynchrony from gated myocardial perfusion SPECT studies. We have validated this technique and shown that it can reproducibly predict the response to CRT in patients with heart failure induced conduction disturbances and ventricular dyssynchrony. This technique has been introduced on the First Taiwan Nuclear Cardiology Symposium. This special review is a follow up of the lecture.