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藥物食品分析 MEDLINESCIEScopus
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| 篇名 | 以高效能液相層析法分析馬兜鈴屬植物所含的馬兜鈴酸及馬兜鈴內醯胺衍生物 |
|---|---|
| 卷期 | 12:1 |
| 並列篇名 | Analysis of the Analogues of Aristolochic Acid and Aristolactam in the Plant of Aristolochia Genus by HPLC |
| 作者 | 周政輝 、 李佳穎 、 林均樺 、 吳天賞 、 Schelonka,Edward P. |
| 頁次 | 40-45 |
| 關鍵字 | 高效能液相層析 、 馬兜鈴酸 、 馬兜鈴內醯胺 、 粉防己 、 廣防己 、 川木通 、 關木通 、 HPLC 、 Aristolochic acid 、 Aristolactam 、 Stephania tetrandra 、 Aristolochia fanchi 、 Clematis armandii 、 A. manshuriensis 、 MEDLINE 、 Scopus 、 SCIE |
| 出刊日期 | 200403 |
中文摘要
英文摘要
A facile reversed-phase HPLC method for the analysis of aristolochic acid (AA) and aristolactam (AL) analogues was developed and used for the quantitative determination and quality control of the traditional Chinese medicine. Homonymic Chinese crude drugs such as Stephania tetrandra ( ) and Aristolochia fanchi ( ), Clematis armandii ( ) and A. manshuriensis ( ) can be easily identified by this method. The quantitative determination of AAs and ALs in 12 species of Aristolochia (A. elegans, A. zollingeriana, A. cucurbitifolia, A. mollis, A. kaempferi, A. shimadii, A. heterophylla, A. debilis, A. foveolata, A. contorta, A. trilobata and A. odoratissima) has been investigated. The chromatograms obtained in this study can serve as fingerprints to identify plant species in the Aristolochia genus, thus avoiding incorrect identification of herbal ingredients in manufacturing traditional Chinese medicine.