一位78歲男性肺鱗狀細胞為患者，在化療和左肺切除術後兩個月後，發生了右足疼痛的現象。鎝-99m-MDP骨骼掃描顯示在右腳有不正常攝取。因為附肢骨的骨轉移不常見，所以我們起初沒有做出骨轉移的診斷。後來MRI檢查顯示在該部位有腫瘤組織，因此病人接受切除手術，病理報告為轉移性鱗狀細胞癌。從這個病例我們學到，在為症患者若骨骼掃瞄出現附肢骨病變，骨轉移的可能性仍無法完全排除。此時需小心安排X光、MRI檢查或組織切片才能做出正確的診斷。

We present a case of squamous cell lung cancer with metastases to cuboid bone. The 99mTc-MDP whole body bone scintigraphy of the patient showed an area of increased tracer uptake at the cuboid bone of his right foot. Because of the rare occurrence of bone metastases to appendicular skeleton， the diagnosis of bone metastasis for this patient was not concluded from this bone scan. Subsequent MRI examination found a tumor mass in the same area. The patient then received wide tumor excision and the metastatic squamous cell carcinoma was confirmed from pathological findings. This case suggests that for malignant patients with anomalous appendicular uptake from bone scan， the possibility of bone metastasis should not be overlooked and further studies such as plain radiography， MRI or biopsy should be arranged.