二十一世紀之醫療照護是以品質為照護之目標，而病人安全更是核心。為提升醫療照護品質；近年來許多醫療品質相關研究對於醫療工作環境中各種不同層面對護理人員與病人安全進行探討，結果顯示醫療機構的工作環境會影響護理人員及病人安全。本文主要目的為以組織氣候整合模式為架構，整合目前文獻中護理人員、工作環境與病人安全相關之研究成果，以提供臨床實務與未來研究方向之參考。

Maintaining high quality is the main goal of healthcare services in the 21st century, and moreover, the patient safety is the core value. A lot of researches have been conducted to investigate the relationship between the work condition and the outcomes of healthcare services as well as the patient safety. Results of the researches indicate that work condition influences both the outcomes of healthcare services and the patient safety. The main purpose of this review is to integrate the relevant evidences from the literature by using the Integrative Model of Organizational Climate as a guide. Directions for future research and clinical implications are recommended based on the evidences reviewed.