光學電腦斷層掃描在三維凝膠劑量計的應用，與X 光電腦斷層掃描有許多的共通點，DeskCAT™掃 描儀的發展是為了用於X 光電腦斷層掃描的教學為目的。NIPAM 聚合型凝膠(NIPAM Polymer gel)劑量計有 高的輻射靈敏度，所以可以做為臨床輻射照射劑量驗證的工具。本研究主要針對利用教學用DeskCAT™做 為n-NIPAM 聚合型凝膠劑量計的計讀工具之研究為目的。研究所使用的n-NIPAM 凝膠由明膠(gelatin) (5%) 、單體(NIPAM)(5%) 、交聯劑(BIS)(3%) ，並加入5 mM 四羥甲基磷(THPC)以排除氧氣。利用直線 加速器給予6 Gy 的劑量，後利用DeskCAT™依不同的掃描條件：不同的切面數800 切面與640 切面；不 同的可見光-紅光與綠光；不同的解析度重組最高解析度(VR)、高解析度(HR)、中解析度(MR)和低解析度(LR) 去做影像的計讀並與治療計畫系統相互比較。結果顯示於劑量深度5 cm~7 cm 不同切面都具有非常好的符 合度，代表各個切面有好的均勻度與一致性。在3%/3 mm 的dose-difference / distance-to-agreement（DTA） 標準之下，凝膠劑量計與TPS 通過率最高為通過率為93.16±1.28。由結果可知得知DeskCAT™不僅具有原 理解說及教學效果，同時具有量測結果的功用。

Optical computed tomography (OCT) for 3D radiation dosimetry has many features in common with x-ray CT. In fact, optical CT scanner- DeskCAT™ was development for the purpose of teaching the principles of x-ray CT. Polymer gel dosimeters have hight radiation sensitivity. The gel can be used as a dosimetric verification tool in clinics. This evaluation study is used DeskCAT™ as the readout tool of the n-NIPAM polymer gel dosimeter. The n-NIPAM was composed of 5% gelatin, 5% monomer, and 3% cross-linker and inserted with 5 mM THPC for deoxygenation. Dose responses of 6 Gy delivered by a linear accelerator were exarnined. In this study, use different scanning conditions to scanned and readout n-NIPAM dosimetry by DeskCAT™. The dose profiles were found to be consistent at the depths of 5.0 cm to 7.0 cm for the gel phantom. The gamma pass rates highest were calculated to be 93.16±1.28 using 3% dose difference and 3 mm distance-to-agreement criterion. The n-NIPAM polymer gel dosimeter was highly spatially uniform. The DeskCAT™ could be used to demonstrate the principle of optical CT for teaching and if further investigated could be a potential optical readout device for gel dosimetry.