肌少症(Sarcopenia) 被視為老年症候群的表現之一，也常見於老年慢性阻塞性肺病 (Chronic obstructive pulmonary disease) 族群，兩種疾病相互間有一些共同的機轉，但複雜的臨 床表現應給予多面向的評估，才能進一步進行預防和治療，以避免不良預後的發生。雖然相 關領域從近年來的文獻發表可見有顯著的進展，但國內外的證據依然有分歧之處，因此希望 藉由這篇綜論來讓我們能更深入了解老年慢性阻塞性肺病族群肌少症的現況。

Sarcopenia can be viewed as a common condition among the geriatric syndrome and occurs in older patients with chronic obstructive pulmonary disease. The complex clinical manifestations remind us of the importance of multidisciplinary evaluation, regarding both prevention and treatment, as to eventually avoidance of adverse prognosis. However, recent clinical evidences still show certain level of divergence and current guidelines could not give us precise recommendation. As the result, we try to add newer insight including more evidence-based results and local reports from Taiwan. We do expect to know more about sarcopenia and its developing interventions and treatments in chronic obstructive pulmonary disease patients. (J Intern Med Taiwan 2016; 27: 233-238)