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放射治療與腫瘤學

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篇名 SALVAGE CONCURRENT CHEMORADIATION THERAPY STABILIZES PROGRESSION OF RECURRENT INTIMAL SARCOMA OF THE LEFT ATRIUM: A CASE REPORT
卷期 23:4
並列篇名 以同步放化療治療復發左心房肉瘤:病例報告
作者 呂隆昇潘佳欣林永和賴欣宜戴承正許哲瑜邱仲峯丁禮莉
頁次 277-284
關鍵字 Concurrent chemoradiation therapy Intimal sarcoma recurrence同步放化療復發性內膜肉瘤TSCI
出刊日期 201612
DOI 10.6316/TRO/201623(4)277

中文摘要

內膜肉瘤是罕見的原發性心臓腫瘤。針對新診斷的內膜肉瘤,目前的標準治療為手術切 除,而針對局部復發的內膜肉瘤,其最佳治療策略尚未有定論。本文報告一例左心房內膜肉瘤 局部復發病例,患者在復發後併用化學治療與同步放化療而得到疾病控制,由初診斷迄今存活 已達48個月。強度調控放射治療在臺灣已相當普及,針對無法手術切除的心臓腫瘤,或可考 慮以此技術配合化療積極進行局部治療。

英文摘要

Intimal sarcoma is a rare primary malignancy of the heart. While surgery is the mainstay of curative treatment for newly diagnosed disease, the role of radiation for local recurrence remains elusive. Here we report a case with locally recurrent intimal sarcoma of the heart in the left atrium. Recurrence has been successfully stabilized with sandwich treatment. The patient survived for more than 48 months since the initial diagnosis and is still alive at the time of manuscript preparation. As intensity modulated radiation therapy is becoming widely accessible in Taiwan, there is an unmet need to document outcome and side effect profiles from aggressive CCRT to primary and recurrent cardiac malignancy.

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