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藥物食品分析 MEDLINESCIEScopus

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篇名 Study on the △3→△2 Isomerization During Preparation of Ceforoxime Double Ester Prodrugs
卷期 1:2
作者 HUI-Po WANGJIA-SHUAI LEE
頁次 145-153
關鍵字 MEDLINEScopusSCIE
出刊日期 199306

中文摘要

英文摘要

△3→△2 Isomerization during preparation of cephalosporin ester prodrugs has been frequently reported. Methods to eliminate the isomerization must be established. In the course of preparing cefuroxime double ester prodrugs, quarternary ammonium salts with different counter ions were usedas catalysts for alkylations and their effects on the isomerization were compared.

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