血脂異常(dyslipidemia) 是現代人常見的營養與新陳代謝問題。由於慢性腎臟病(chronic kidney disease) 患者對於血脂的新陳代謝與腎臟功能正常者有所差異，血脂異常於慢性腎 臟病患者也比一般族群更為常見。本文根據近幾年來針對慢性腎臟病患者之血脂異常的大 規模臨床試驗結果，將針對下列三個相關主題進行文獻回顧：(1) 慢性腎臟病與心血管疾病 (cardiovascular diseases) 的相關性，(2) 慢性腎臟病對於血脂肪新陳代謝之影響，與(3) 慢性腎 臟病患者血脂異常之治療指引及藥物選擇。

In general population, dyslipidemia has become a common health condition concerning the nutrition and metabolism. Chronic kidney disease (CKD) patients are observed to harbor dyslipidemia much more often than those with normal renal function. Therefore, based on the results of many clinical studies completed during the past decade, this article aims to conduct a systemic review on three fields: (1) the relationship between CKD and cardiovascular disease; (2) the effect of CKD on lipid metabolism; and (3) the current recommendations on the management of dyslipidemia in CKD patients. (J Intern Med Taiwan 2018; 29: 107-121)