本研究目的在探討大腸直腸癌症病患生活品質情形與各項治療措施等相關因素對其生活品質之影響程度。自民國82年11月16日至83年01月31日以修訂之生活品質指標(QLI)、健康控制重心及自行設計之間卷，調查某醫學中心之大腸直腸癌症病患。發出問卷245份，回收211份，其中有效問卷共205份。所得資料以SAS/PC進行資料分析。結果發現:大腸直腸癌症病患的整體生活品質指標得分為20.85分，顯示病患具有中上程度之生活品質。在生活品質所涵蓋的範園中，以家庭因素的得分最高;環境因素得分最低。大腸直腸癌病患的生活品質與人工肛門之有無顯著差異，病患的生活品質指標與所獲得的心理支持滿意度呈正相關，與腫瘤所造成的身體症狀及治療創作用呈負相關。在健康控制重心方面:病患的內在自我控制型特質與生活品質指標間呈正相關，而與機運控制及重要影響人士控制型特質無關。大腸直腸癌病患的『內在自我控制型特質』、『對所獲得心理支持的滿意度』、『人工肛門之有無』、『腫瘤所造成身體之症狀』為其生活品質的最佳預測因素。

The main purposes of this survey were to investigate the levels of quality of life of the colorectal cancer patients and to identify its influencing factors. The modified Quality of Life Index (QLI), Health LocusControl(HLC), and a self-designed questionnaire were used for data collection from Nov. 1993 to Jan. 1994. A total of 245 questionnaires were distributed. However, only 205 valid questionnaires were used for data analysis.
The results found that the overall QLI was 20.85, indicating moderate level of quality of life. In each dimension of QLI, the highest one was "family dimension" and the lowest one was "environmen-tal dimension". Nevertheless, the levels of QLI were affected by variables such as:"existence of colostomy" ; "psychological support"; "symptoms of cancer"; and "treatment side-effects".
In regard to each dimension of the health locus of control, the overall quality of life was only posi-tively related to the "intemal locus of control". The result of stepwise regression also showed that "in-temal health locus of control", "satisfaction of psychological support", "existence of colostomy", "symptoms of cancer" were significant predicators for the overall quality of life of this specific group of patients.