本研究目的旨在探討血液透析病人疲倦感與社會支持、憂鬱傾向及血淚生化檢驗值的相關性，以立意取樣方式共收取110位末期腎臟功能衰竭，且長期接受血液透析治療的病患。研究工具包括:疲倦感問卷、社會支持問卷、貝氏憂鬱量表及血液生化檢驗;採皮爾遜積差相關、獨立樣本t考驗、單因子變異數分析、卡方檢定與逐步複迴歸分析為統計方法。研究結果顯示:(1)血液透析病人的疲倦感嚴重度是傾向於輕度至中度。(2)疲倦感嚴重度與憂鬱傾向呈正相關(r = 0.25, p< 0.05)，憂鬱傾向可作為疲倦感的預測因子，共可解釋28.65%的變異量。(3)人口學變項、社會支持、血液生化檢驗值與疲倦感嚴重度無關。

The purpose of this study was to analyze 110 hemodialysis patients' fatigue and to find out the relationship between fatigue and the other variables. The independent variables were depressive mood, the provision of social support and the index of blood biochemical data. The subjects were in the end stage of renal failure with long term hemodialysis treatment in hemodialysis centers. The tools used were as follows: fatigue scale, social support questionnaire, Beck Depression Inventory (BDI) and biochemical laboratory data. The statistic methods used were based on the Pearson product-moment correlation, independent t test, one-way ANOVA, X2 test and multiple regression. The results were as follows: (1) The degree of fatigue was mild to moderate. (2) The fatigue was significantly associated with depression, with a correlation coefficient of 0.52 (p < 0.05). The predictor of fatigue in this study was depression, which would explain 28.65% of total variance of hemodialysis patients' fatigue. (3) The degree of fatigue was not associated with demographic variables (i. e.: sex, age, marriage, duration of hemodialysis treatment, education), nor with blood biochemical data or social support.