本研究目的在探討接受門診治療之愛滋病毒感染者之生活品質及其相關因素，係為描述相關性研究設計。採立意取樣方式在台北三家醫學中心及一家性防治所門診，共選取114位個案，以基本屬性量表、生理症狀困擾量表、情緒困擾量表、社會支持量表、生活品質量表收集相關資料，並以描述性統計、皮爾森積差相關及複迴歸等方法進行處理。研究結果顯示整體生活品質之平均得分為18.50；在家庭層面之得分最高，而經濟環境層面最低。生理症狀困擾及情緒困擾與生活品質呈顯著負相關；社會支持與生活品質呈顯著正相關。生理症狀困擾與情緒困擾呈顯著正相關；情緒困擾與社會支持呈顯著負相關；生理症狀困擾與社會支持呈顯著負相關。最佳預測生活品質之變項包含：情緒困擾、社會支持、自覺感染途徑、生理症狀困擾、主要經濟來源，可解釋整體生活品質之變異量達60.9%。而其中情緒困擾為影響生活品質之最重要因素，因此建議提供愛滋病感染者有品質之照護時，減輕情緒困擾為首要工作。

The purpose of this study was to identify the variables related to quality of life in the population of indi vid u als liv ing with HIV/AIDS (PLWHA) in Taiwan. Purposive sampling was used to identify subjects from the outpatient departments (OPD) of three teaching hospitals and one sexually transmitted disease (STD) clinic in the Taipei area. For this study, the questionnaire included a demo graphic data sheet, phys i cal-symptom dis tress and mood-disturbance scales, a per sonal-resource questionnaire (PRQ85-II) and a quality-of-life index (QLI). A total of 114 subjects completed the questionnaire. The results revealed that higher quality of life was associated with less mood disturbance (r = -.72; p < .001), reduced physical-symptom distress (r = -.47; p < .001), and higher levels of social support (r = .57; p < .001). PLWHA life quality was reflected accurately by mood disturbance, social support, physical-symptom distress, self-perceived mode of HIV transmission, and major source of financial support. These variables accounted for 60.9% of QOL variance. As mood disturbance was the strongest predictor of quality of life, psychosocial intervention for mood disturbance should be emphasized and developed in future studies.