目的：Leipzig Applicators 為 Nucletron Micro-Selectron Ir 高劑量率後荷治療機配件之一，依射源之方位可分為直立式及水平式二種型式，又依其口徑大小各可分為一、二及三公分之裝療管。為了解此型裝療管的臨床劑量學特性，本實驗將量測五種特性，分別為：幾何結構、相對輸出、百分深度劑量、等劑量分佈曲線及真實矢狀面輻射洩漏情形。 材料與方法：以高精密度游標尺量取各裝療管之幾何結構。相對輸出則以 HN.E.0.03 cc平板型 (type:2534) 游離腔連托 lonex Dosemaster 2590 電位計，加上 3 mm 增建層予以測量， 並歸一到在全假體內相等距離所測得的輸出。 百分深度劑量及等劑量分佈曲線則以Scanditronix RFA-300 水假體連接 p- 型電子射束半導體偵測器在水中測量而得。 輻射洩漏量的測量則於 Kodak V-film 中間，依裝療管之外形挖空，將底片置於裝療管矢狀面，上下各置 0.5 cm bolus 作增建，以測量真實矢狀面之輻射洩漏量。結果：水平式裝療管之輸出增加約 10%，直立式裝療管則降低約 9%。 有效射源至表面距離； 水平式裝療管為 1.93cm，直立式則為 1.74 cm。直立式裝療管之等劑量分佈曲迫中心軸有凹陷情形。水平式裝療管之輻射洩漏量為最高劑量點之 30%，位於裝療管的項部，而直立式之輻射洩漏量為最高劑量點之 20%，位於裝療管的側部。結論：Leipzig applicators 由於體積小，適合於一些小範圍皮膚癌，口腔癌，及其他癌症之治療。由測量的結果發現：百分深度劑量可用有效射源至表面距離予以準確估算至 20% 劑量深度，直立式與水平式裝療管的輸出變化達 10%， 投予劑量時應特別注意。輻射洩漏量的測量提供使用者了解裝療管的防護能力偶熱點所在位置，以供臨床應用時之參考。[ 放射治療與腫療學 1997; 4: 133-137]

　　　　　Purpose: Leipzig applicators are one kind of accessories of NucletronIr High-Dose-Rate remote afterloading system. According to the orientation ofthe source axis in the applicator, it can be divided into two kinds: horizontaland vertical ones. There are three kinds of diameter foreach type of applicator:1,2 and 3 cm. Five characteristics ofthe applicator will be measured forclinical application. They are geometric structure, relative relative output,percent depth dose, isodose curve distributions and real sagittal planeradiation leakage test. Material and Methods: High accuracy calipers was used tomeasure the geometric structure of the applicator. The relative outputs weremeasured with N.E. 0.03 c.c. parallel-plate ionization chamber connected toIonex Dosemaster 2590 in RMI solid phantom with 3 mm build-up layer. The outputswere normalized to the dose in full phantom that was measured at the samesource-to-chamber distance. The percentage depth dose and isodose curvedistrubutions were measured with Scanditronix RFA-300 water phantom connected top-type electron beam semiconductor chamber. The measurement was performed inwater along the side Mylar window. The real sagittal plane radiation leakage ofthe applicator was measured with Kodak V-film that was cut according to theshape of the applicator. Results: The relative outputs of the horizontal typewere increased 10%, while the vertical ones were decreased 9%. The effectivesource-to-surface distance of the horizontal type is equal to 1.93 cm and 1.74cm for the vertical ones. the isodose curves are attenuated in the central axisof vertical type applicators due to the attenuation from catheter and sourcetip. The hot spots of the horizontal type applicators are located at the top ofthe applicator and at the sides for the vertical ones. The leakage is 30% forthe horizontal types and 20% for the vertical types. Conclusion: Leipzigapplicators can be used to treat some small volume cancer such as skin cancer,oral cancer and forother dose boost treatment. The dose can be estimated withESSD to approximately 20% depth accurately. The hot spots of the applicatorsallow the user to avoid unnecessary exposure. [Therapeut Radiol Oncol 1997; 4:133-137]