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放射治療與腫瘤學

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篇名 放射手術與多照野放射治療早期復發性鼻咽癌之臨床病例報告
卷期 4:1
並列篇名 Radiosurgery and Multiple Co-Planar Fields in the Treatment of Recurrent Nasopharyngeal Cancer--A Case Report
作者 白冰清曾雁明劉千如李石增湯國政
頁次 65-69
關鍵字 復發鼻咽癌立體定位X光刀放射治療Recurrent nasopharyngeal cancerStereotactic radiosurgeryRadiotherapyTSCI
出刊日期 199703

中文摘要

     目的:復發鼻咽癌接受立體定位 X 光刀及同平面七照野體外放射治療,追蹤達 32 個月之病例報告。材料與方法:病例為接受放射治療後一年發生復發之鼻咽癌患者,其接受了二度空間同平面七照野之體外放射治療,劑量為 50.4 Gy。 再接受立體定位 X 光刀,取 2 個等劑量中心,治療體積為 41.75 立方公分,給予劑量於 80% 等劑量曲線處為 10 Gy。結果:復發腫瘤治療後追蹤 32 個月仍無局部腫瘤進行的跡象,以及相關後遺症的產生。結論:在追蹤 32 個月後,仍維持局部腫瘤的控制,亦無相關後遺症產生。比起對復發鼻咽癌傳統的治療,包括手術、化學治療、放射近接治療及體外放射治療而言,多照野體外放射治療合併之立體定位 X 光刀手術,在不降低局部腫瘤之控制下可減少後遺症。 但仍需要長期評估對末期反應組織之影響。

英文摘要

     Purpose:To report a case of locally recurrent nasopharyngeal cancer (NPC) remaining disease-free 32 months after 7 portals of co-planar external beamsMaterials and Methods: A NPC patient recurred at one year after the first localirradiation. He then was treated with a dose of 50.4 Gy external radiotherapydelivered by 7 portals of co-planar beams and followed by 10 Gy LINAC-basedstereotactic radiosurgery. In radiosurgery, the dose was delivered by using of2 isocenters and prescribed at the 80% isodose curve. The treatment volume was41.75 cubic centimeter.results:After 32 months of follow up, no local recurrence or adverse effect isrecognized.Conclusion: Multiple portals of co-planar external beam radiotherapy andradiosurgery in treating recurrent NPC is successful in local control and lesscomplication than single treatment modality such as operation, chemotherapy,brachytherapy and regular external radiotherapy. Long-term follow up isnecessary for further evaluation in late effect on critical organs of this kindof combined treatment modalities.

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