目的：評估放射治療對於晚期非小細胞肺癌病人之適當性。材料與方法：共有 89 名病患於 1992 年 7 月至 1997 年 6 月間到馬偕紀念醫院求診。其中 63 位曾接受放射治療，另外 23 位則否。對於第三期之病患將給予胸腔放射治療，而第四期之病患則只針對轉移部位或引起之症狀給予放射治療。結果：相對於沒有接受放射治療的病人比較起來，晚期非小細胞肺癌病人接受放射治療並沒有存活率增加之優點。結論：胸腔放射治療並不能增加晚期非小細胞肺癌病人之存活率。

　　　　　Purpose:To re-evaluate the appropriateness of thoracic radiotherapy(RT) for patients with advanced non-small cell lung cancer (NSCLC). Materialsand Methods:This retrospective study included 89 patients with advanced NSCLCregistered in Mackay Memorial Hospital from July 1992 to June 1997. Thoracic RTwas given with radical or palliative intent depending on the stage and/orperformance status at diagnosis to 63 (the RT group) but had withheld in 26 (thenon-RT group). The total dose to the primary tumor was in the range of 5000-6000cGy at 180 cGy per fraction over 5-6.5 weeks. Tumor control was strictly definedas complete disappearance of tumor on all radiographic examinations and/or noevidence of disease clinically at the last follow up. Results:No survivaladvantage was noted in the RT group compared to the non-RT group (median 3.0 vs.5.5 months). The mean survival time of patients with stage Ⅲ disease was 11.37± 1.94 months and median survival time was 8 months. The control rate in the RTgroup was poor with only 4 of 63 (6%) disease-free on the last follow up. One offour patients who were disease-free died of radiation pneumonitis about 3 monthsafter complete of RT. In addition, one patient with stage lllb was still alive,undergoing chemotherapy for distant metastasis. Conclusion:Thoracic RT did notprolong survival for patients with locally advanced NSCLC.