白質結學是鑑定生物分子三空間結構的最有力工具之一，配合同步輻射光的高亮度及能量可調性，可以大幅提昇生物分子的結構鑑定速度，足以滿足基因體學及藥物設計等需要大量分子結構資料等研的需求。為此，因家同步輻射研究中心特別興建兩座高效能蛋白質結晶學光束線，其中一座為針對未知蛋白質結構解析用途，能量範圍從6.5至19仟電子伏特(keV)之多?長異常繞射(MAD)光束線，另一座為供晶體篩選、藥物設計以及高解析度結構分析用，能量為12至14仟電子伏特之單色光(mono)光束線。使用最成熟可靠的光束線技術，配備最先進的面積偵測器系統、高速高效能的計算及網路環境、自動化的樣本裝卸系統，及友善的數據收集與控制系統，MAD光束線一年約可收集800組MAD數據，單色光光束線一年約可收集1200組高解析度數據。

Protein crystallography is one of the most powerful and dominant tools to determine the three-dimensional structures of biological macromolecules today. In order to increase the rate of crystal structure determination, the highly brilliant and easily tunable synchrotron radiation (SR) X-ray source is essential to meet the needs of abound structural information for studying structural genomics and structural-based drug designs. To satisfy these requirements, the Natioanl Synchrotron Radiation Research Center (NSRRC) has constructed two dedicated Synchrotron Radiation Protein Crystallography Facility (SPXF) high-throughput beamlines for structural genomics research. One of the beamlines will be a multi-wavelength anomalous diffraction (MAD) beamline with energy tenability from 6.5 keV to 19 keV for unknown structure determinations, and the other will be a monochromatic (MONO) beamline with energy from 12 keV to 14keV for crystal screening, drug design and high-resolution structure studies. The well-devleoped light source technique, advanced area detectors, high-efficient computing and network environments,automatic crystal sample changing and centering, and user-friendly data collection and control stystems will produce 800 MAD data set per year for MAD beamline and 1200 useful data sets per year for mono beamline. .