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中華公共衛生雜誌

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篇名 聚氯乙烯工人GST T1,GST M1及CYP2E1基因型與其肝功能之相關研究
卷期 16:6
並列篇名 The Relationship Between the GST T1,GST M1,CYP2E1 Genotype and Abnormal Liver Function in Pvc Workers
作者 黃忠英鄭尊仁黃國良王榮德謝玲玲
頁次 499-512
關鍵字 氯乙烯麩胺基硫轉移?細胞色素P450 2E1肝功能VinylChlorideGlutathione s-transferasesCYP 2E1Liver functionTSCI
出刊日期 199712

中文摘要

     本文目的是以統計模式之建立為出發點,對每天之平均及累積住院費用進行分析,探討腦中風病患由急性醫院「轉診」至長期照護機構之臨界日。在病患住院初期,進行大部份的檢驗及急性治療,住院費用最高,待病情較穩定,不需要急性醫院的醫療設備後,費用便會下降。因此,基於病情能反映於費用上的假設,對住院費用及住院天數進行兩段迴歸分析,前後兩段之迴歸線斜率差異為最大、或前後兩段平均費用差距最大,便可視為轉診的臨界日。除此之外亦可以累積住院費用達某百分比 (如 75%,80% 或 90%) 時作為切點討論。 研究之樣本來自於臺灣北部某醫學中心, 共 1,357 人, 平均住院 22.9 天、住院費用76.325 元。若以兩段迴歸法分析,則大部份可以在三至五天轉介: 若以總住院費之 75% 、80% 或 90% 作為轉診臨界日, 則平均亦不過 12 至 13 天,比目前平均住院的 23 天仍短很多。若能適時轉診,營運增長率可達 12% 至 34% 不等。因本研究僅以費用計算,並未參考病人之病情徵狀,故建議後續之探討朝此方向進行,並結合「費用」與「病情」兩大項目之分析結果綜合討論,以期能更有效運用有限之醫療資源。

英文摘要

     A few statistical models were constructed to investigate the mostappropriate time to refer hospitalized CVA patients from a medical center tolong term care institutes. Based on the assumption that patients' physical con-ditions can be reflected in their hospital fees, the cumulative charges wereexamined by a two-piece regression. It is perhaps most efficient, from hospitalmanagement's point of view, to transfer patients at the time where the dif-ference between the slopes of the regression lines before and after this pointis maximized. Alternatively, one can also maximize the difference in averagedaily charges before and after such point, or when the cumulative charges reach,say, 75%, 80% or 90%. The studied sample consisted of 1357 CVA inpatientsrandomly drawn from a medical center in northern Taiwan. Their average length ofstay (LOS) was 22.9 days, with a mean hospital fee of NT$76325. Results of thepiecewise regression analysis show that most patients can be referred in 3 to 5days. On the other hand, we also found that 75%-90% of the total fee wasaccumulated in the first 12-13 days. Should patients be transferred with-in thederived days, operating efficiency can increase by 12%-34%. Since only fees areused in the modeling process as the dependent variable, but physical conditionsand outcomes of the patients have been largely ignored, results of this researchcan by no means be considered complete. Yet this still seems to be one of thepioneer projects investigating

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