背景：鎝(V)-99m-DMSA為一種新的腫瘤檢查用核醫造影劑，臨床上被用於偵測惡性腫瘤或某些發炎性疾病。本研究之目的在比較鎝(V)-99m-DMSA和鎵-67-檸檬酸鎵對於淋巴癌檢查的可用性。
方法：12位未經治療的惡性淋巴癌病人 (7位男性與5位女性，年齡24~78歲)，其中3位為何杰金氏淋巴瘤(Hodgkin's lymphoma)、8位為非何杰金氏淋巴瘤(non-Hodgkin's lymphoma)，另一位則是MALToma。所有病人都先接受全身性鎝(V)-99m-DMSA腫瘤造影檢查，並於3~4天後再接受鎵-67-檸檬酸鎵腫瘤造影檢查。
結果：所有病人的鎵-67-檸檬酸鎵腫瘤造影檢查結果都呈陽性，而鎝(V)-99m-DMSA腫瘤造影檢查卻未發現任何病灶。
結論：雖然鎝(V)-99m-DMSA和鎵-67-檸檬酸鎵都可用於偵測某些惡性或發炎疾病，然而對於偵測淋巴癌而言，鎝(V)-99m-DMSA顯然沒有臨床可用性。

Background: Pentavalent 99mTc-dimercaptosuccinic acid (99mTc(V)-DMSA) is a new tumor imaging agent which has been used to image not only in various malignant tumors, but also in some inflammatory diseases, in competition with gallium-67 citrate (67Ga). This study was undertaken to compare the clinical value of 99mTc(V)-DMSA and 67Ga in lymphoma patients.
Methods: Twelve patients (7 men and 5 women ranging in age from 24 to 87 years) with malignant lymphoma (3 Hodgkin's lymphoma, 8 non-Hodgkin's lymphoma and one MALToma) without any treatment were included in this study. In all patients, a whole body 99mTc(V)-DMSA scan was obtained initially. Subsequently, comparative whole body 67Ga scan was performed 3-4 days apart. Results: 67Ga scan was positive in all lymphoma patients; however, no any lesion was detected by 99mTc(V)-DMSA scan.
Conclusion: 99mTc(V)-DMSA scan is of no any clinical value for the detection of lymphoma, although it can detect some other malignant or inflammatory diseases when comparison with 67Ga.