前言：川崎病是好發於嬰孩之急性發熱性疾病，對冠狀動脈的影響嚴重程度與疾病的預後很有關係。本試驗之目的是希望找出一個非侵犯性之檢查，以便早期診斷川崎病之心臟疾患。
方法：27位患有川崎病之小孩被包括在這個試驗，由小兒心臟科醫師對所有病患進行心臟超音波檢查，以評估是否有冠狀動脈瘤之病變。另外，所有病患亦接受鉈-20l心臟單光子射出電腦斷層攝影，以評估冠狀動脈心肌灌注之異常與否。
結果：(1)12/27(44.4%)病患沒有冠狀動脈瘤，而15/27(55.6%)病患有冠狀動脈瘤；(2)12/27(44.4%)病患冠狀動脈心肌灌注正常，而15/27(55.6%)病患冠狀動脈心肌灌注之異常；(3)7/27(25.9%)病患鉈-201心臟單光子射出電腦斷層攝影及心臟超音波皆正常，5/27(18.5%)病患只有心臟超音波異常，5/27(18.5%)病患只有鉈-201心臟單光子射出電腦斷層攝影異常，10/27(37.0%)病患鉈-201心臟單光子射出電腦斷層攝影及心臟超音波皆異常。
結論：大郎分患有川崎病之小孩有冠狀動脈瘤之病變成冠狀動脈心肌灌注之異常。然而，冠狀動脈瘤之病變與冠狀動脈心肌灌注之異常並沒有統計上之明顯相關性。

Backgrounds: Kawasaki disease (KD) is an acute febrile disease in infants and children. Its prognosis correlates with the severity of coronary involvement. The aim of this study is to establish a noninvasive diagnostic method for early assessment of cardiac involvement in Kawasaki disease.
Methods: Twenty-seven children with Kawasaki disease (KD) were included in our study. The presence of abnormal coronary arteries (CA) with coronary aneurysm was determined by an experienced pediatric cardiologist using two-dimensional echocardiography (2D-Echo). Dipyridamole-redistribution thallium-201 (201TI) single photon emission computed tomography (SPECT), a noninvasive method for the assessment of myocardial perfusion, was performed in these 27 children for comparison with 2D-Echo findings.
Results: (1) 12/27 (44.4%) cases had no aneurysm and 15/27 (55.6%) had significant aneurysms; (2) 12/27 (44.4%) cases had normal perfusion and 15/27 (55.6%) had significantly abnormal perfusion; (3) 7/27 (25.9%) cases showed normal 2D-Echo and SPECT findings, 5/27 (18.5%) showed abnormal 2D-Echo findings only, 5/27 (18.5%) showed abnormal SPECT findings only, and 10/27 (37.0%) showed abnormal 2D-Echo and SPECT findings.
Conclusion: Most of the KD children in this study had aneurysms or abnormal perfusion. However, no significant correlation was observed between the existence of coronary aneurysms and abnormal myocardial perfusion.