目的：本研究係探討於人體表面進行放射治療時，製作完全貼附人體3D適形填充物之生成模組。其係整合逆向工程(Reverse Engineering)與人體數位模型系統之3D取像及成形技術，使用兩種快速成型機(Rapid Prototyping)製作密度不同之材料。材料與方法：本研究使用塑膠粉末(PVC)膠合及液態樹脂(ABS)燒結成型填充物，以符合個案之人體3D適形填充物(bolus)實體。結果：本研究之3D適形填充物可完全貼附人體，可有效改變放射劑量深度，進而使皮膚劑量達到處方劑量。結論：該3D適形填充物之製程經本研究之執行及驗證，可以標準作業程序生成模組，生成最佳化之3D適形填充物實體，希望在未來能提供放射治療輔助器材另一種選擇。

Purpose: This study shown the 3D total contact bolus of human body can effectively improve the radiation dose of the skin surface during radiotherapy. Material and Methods: When the 3D total contact bolus of human body be produced, we integrated 3D image and reverse engineering technology to a 3D Anthropometric Phantom Study, and used rapid prototyping technique to produce a 3D total contact bolus entity to the human body. Results: We have selected two materials in order to test which one is better for skin dose coverage. According to our study, 3D total contact bolus made by ABS (ACRYLONITRILE-BUTADIENE-STYRENE) can get the correct prescribed dose on skin surface. Conclusion: The manufacture process of 3D total contact bolus of human body can be an optimized standard operating procedure and it will be a useful tool for radiotherapy.