約有25％的急性胰臟炎個案會發展成重度，造成生命的威脅，死亡率由3％增至31％，早期的評估篩檢，成為臨床照護重要的議題。本文將介紹目前臨床上常用於急性胰臟炎嚴重性評估的不同方法，並比較其優劣。臨床上常用Ranson's Score、Modified Glasgow Critera、檢驗C-反應蛋白(CRP)的值來評估急性胰臟炎嚴重性，但前述方法須等候48小時；此外亦使用電腦斷層掃描，但會大幅增加醫療成本；建議在入院時使用APACHE-Ⅱ Score當分數大於7及檢驗介白質6(IL-6)＞400 pg/ml之個案可能發展成嚴重病情，提供臨床工作人員參考，以期早期篩檢並及時提供相關照護。

Up to 25% acute pancreatitis patients may turn to severe life threatening condition. The mortality rate ranges from 3% up to 31%. Early screen patients at risk of developing critical condition remain important issue in the clinical practice. Ranson's Score, Modified Glasgow Criteria, laboratory test C-reactive protein and CT scan can determine severity in patients with acute pancreatitis. However, the previously mentioned score need to wait for 48 hours and the CT scan will increase the health care cost. It is suggest to use the APACHE-II score ＞7 and laboratory test IL-6＞400 pg/ml at the time of hospital admission as a early prediction. Those information can provide a professional update for this potentially complex situation and thus offer appropriate support to promote future health.