本研究目的在調查臺灣地區動物（乳牛和魚?）?源鏈球菌對?種抗菌劑之感受性。2003?至2004?共收集248株鏈球菌，?用藥物感受性試驗檢測對azithromycin (Azi)、clarithromycin (Clar)、erythromycin (Ery)、spiramycin (Spir)、amoxicillin (Amo)及enrofloxacin (Enro) 是否具有抗藥性?結果顯示248株鏈球菌對Spir 的抗藥性最高(100％)，其餘藥物感受性之次依序為：Enro(98.4％)、Clar(87.5％)、Ery(54.8％)、Azi(31.9％)及Amo(21.8％)。研究發現鏈球菌之抗藥性?型：由哺乳?分?之鏈球菌株以Azi-Clar-Ery-Spirr所佔比?最高 (27.5％)，然而由水生動物分?之鏈球菌以Spirr 所佔比?最高 (55.1％)。

The aim of this investigation was to study the antimicrobial susceptibility of 248 Streptococci strains obtained from cattle and fish in Taiwan from 2003-2004. The susceptibilities of 248 Streptococci strains were determined by the agar dilution method to 6 antimicrobial agents included azithromycin (Azi), clarithromycin (Clar), erythromycin (Ery), spiramycin (Spir), amoxicillin (Amo), and enrofloxacin (Enro) in this study. The results indicated that the highest resistant percentage of 6 antimicrobial agents was Spir (100.0%), followed by Enro (98.4%), Clar (87.5%), Ery (54.8%), Azi (31.9%), and Amo (21.8%) among 248 Streptococci strains. The highest percentage of resistant-antimicrobial agent patterns for Streptococci strains obtained from mammals and aquatic organisms were Azi-Clar-Ery-Spirr (27.5%) and Spirr (55.1%), respectively.