隨著奈米量測技術日趨精進，細胞物理性質方面研究正逐步萌芽發展，本文著重於細胞物理性質探討，並從力學觀點，解釋細胞的機械特性及其對組織生理之影響，進而瞭解細胞是如何經由相關力學行為，促使細胞與基材之間產生交互作用，誘發各種細胞生理機制。

Along with the advancement of analytic tools at nano scale precision, scientists gain access to the biophysical properties of the cells. Interpretation of physiology and pathology from interplay between cell, tissue and the physical mechanical alterations of its microenvironment become feasible. The nanotribology opened a new era in
biomedicine from the bottom and now we know that cell-cell interaction and cell-extracellular matrix adhesion as well as the physical forces induce a complex biochemical process and gene expression regulation and ultimately contribute to the phenotype observed. This paper aimed to provide a comprehensive review of the nano/micro technologies developed for the measurement of biophysical properties of cells and the biophysical bases of the cell.