高場不對稱波形離子移動能譜術，為一種可在大氣壓環境下分離氣態離子之新技術，其優點為可減少背景之干擾、增加分析之訊號雜訊比，以及具有分離同分異構物之能力。本文將介紹高場不對稱波形離子移動能譜術之原理及影響分析結果之相關參數，並將對於該技術在藥物分析、同分異構物分離以及蛋白質體學之應用作一簡單回顧。

High-field asymmetric waveform ion mobility spectrometry (FAIMS) is a new technique for gas phase ion separation at atmospheric pressure. The advantages of FAIMS are reducing the effect of background, improving
signal-to-noise ratio and separation isobaric isomers. This paper introduces the theory of FAIMS and the parameters affecting the analytical results. The applications of FAIMS in the drugs analysis, isobaric isomer separation and proteomics are also reviewed.