背景　研究對象為某區域教學醫院之血液透析室病患共114位。目的　在探討血液透析病患的血液檢驗值與睡眠障礙、憂鬱程度及其生活品質相關性。方法　採橫斷式描述相關性研究，由研究者以「基本資料表」、「匹茲堡睡眠品質量表」、「貝氏憂鬱量表」及「臺灣版世界衛生組織生活品質量表」收集資料，以SAS 9.0版套裝軟體進行統計分析。結果　在睡眠障礙方面，女性、糖尿病病患呈現睡眠障礙情形；血比容、鈉值、副甲狀腺素及尿酸等異常，皆與睡眠障礙呈現明顯相關。血液透析病患有60%呈現憂鬱狀態，高密度脂蛋白、三酸甘油酯、鈉值、尿酸，與憂鬱程度都呈現統計上的正相關(p<05)。在生活品質方面以環境範疇得分最高，社會範疇得分最低，教育程度低、糖尿病及部分血液檢驗值異常與生活品質呈現相關。睡眠障礙與憂鬱程度、生活品質呈現明顯相關(p<.05)。結論　病患的基本屬性及血液檢驗值的異常，會影響血液透析病患的睡眠品質、憂鬱程度及生活品質，生活品質也會影響睡眠品質及憂鬱程度。本研究結果，期望協助醫護人員在進行血液透析治療期間，能依據病患的檢驗數據調整透析醫囑、加強透析飲食、體重控制及生活照護之個別性護理指導，以提升醫療照護品質之參考。

Background: This study was designed to analyze relationships among blood test results, sleep disturbance, depression and quality of life in hemodialysis patients. A total of 114 hemodialysis patients treated at a local teaching hospital in Central Taiwan participated. Methods: Using a cross-sectional descriptive correlational approach, the researcher employed several questionnaires, including WHOQOL-BREF, Beck depression inventory-Ⅰ, Pittsburgh sleep quality index and PSQI to obtain study data. Statistical analysis was performed using SAS 9.0. Results: Sleep quality: female and diabetic patients suffered from relatively more severe sleep disturbance. Patient hematocrit, calcium, cholesterol, sodium, ferritin, parathyroid hormone and uric acid levels were all highly correlated to sleeping disorders. Depression severity: 60% of hemodialysis patients suffered from depression. HDL, TG, Na and UA serum levels correlated positively to depression severity (p<.05). Quality of life: participants earned the highest scores in the environmental profile and lowest scores in the social profile. Lower levels of education, diabetes and blood test result abnormalities were found to relate positively to patient quality of life. Severity of participant sleep disturbance and depression were highly related to life quality (p<.05). Conclusions: Participant variables and blood test result abnormalities were found to affect sleep quality, depression severity and life quality. Life quality was also found to affect sleep quality and depression severity. This research was intended to provide guidance to nursing staff to adjust doctors' orders and diet, weight control and daily care recommendations in order to improve nursing care quality and patient life quality during hemodialysis treatment.