背景：代謝症候群是許多心血管危險因子的集合，代謝症候群可能因相關疾病而耗費大量醫療資源。以預防醫學的角度而言，有必要針對代謝症候群進行早期診斷以有效治療。
目標：透過員工健康檢查，探討醫療從業人員代謝症候群盛行率及相關因子是否具有性別差異。
方法：以北部某醫學中心的員工健檢資料庫為代謝症候群分析基礎，以了解員工代謝症候群的現況。代謝症候群的標準是依照九十六年衛生署所修改的新標準，因體檢結果的限制，以總膽固醇取代高密度脂蛋白膽固醇。
結果：本研究對象共1203人，其中男性424人(35. 2%)，女性779人(64.8%)， 平均年齡為40.20±10.59歲。代謝症候群盛行率為16.3%，男性盛行率(24.8%)顯著高於女性(11.7%)(p<0.01)。針對代謝症候群各異常指標分類組成分析，發現男性以血壓、三酸甘油脂及總膽固醇量(3.5%)之組合所佔比例為最高，女性所佔最高比例則為腰圍、血壓及總膽固醇(2.2%)。以邏輯斯迴歸分析發現在控制干擾因子之後，與代謝症候群有關因子具性別差異，腰圍異常為影響男性(OR=1.16, 95%CI: 1.09-1.24)及女性(OR=1.12, 95%CI: 1.04-1.21)與代謝症候群最主要相關因子。
結論：代謝症候群盛行率雖有性別差異，腰圍為影響代謝症候群最主要相關因子。日後有必要加強醫療人員運動及改善飲食習慣，有效控制中央型肥胖，以預防代謝症候群的發生。

Background. Metabolic syndrome is a cluster of cardiovascular risk factors. The complica-tions of metabolic syndrome could consume many medical resources. From the viewpoint of preventive medicine, it is essential for early diagnosis and appropriate treatment to subjects
with metabolic syndrome.
Objectives. To explore the gender difference of the prevalence and associated risk factors of metabolic syndrome among hospital staff based on the health examination.
Methods. To understand the morbidity of metabolic syndrome, we analyzed the database of the health examination of the workers in a medical center on the northern Taiwan. The defi-nition of metabolic syndrome is according to the criteria proposed by Department of Health in 2007, Taiwan. Due to the limitation of the examination, the total cholesterol is used to replace the HDL-C value.
Result. There are 1203 subjects (male: 424(35.2%) and female: 779 (64.8%)) included in this study. The mean age is 40.20±10.59 years. The prevalence of metabolic syndrome is 16.3% and male (24.8%) is significant higher than female (11.7%) (p<0.01). Based on the components of the abnormal criteria of metabolic syndrome, the results show that the highest proportion is higher blood pressure, higher triglyceride, and higher total cholesterol (3.5%) in male and higher waist circumference, higher blood pressure, and higher total cholesterol (2.2%) in female. From the multiple logistic regression, gender difference is found in associated fac-tors related to metabolic syndrome after adjustment for confounding factors. The abnormal waist circumference is the most significant risk factor related to metabolic syndrome both in the
male (OR=1.16, 95%CI: 1.09-1.24) and in the female (OR=1.12, 95%CI: 1.04-1.21).
Conclusion. The prevalence of metabolic syndrome showed the gender difference in this study. Higher waist circumference is the most significant risk factor related to metabolic syn-drome. In order to prevent the incident metabolic syndrome, to encourage hospital staff with
the exercise habit, dietary improvement, and controlled central obesity is important.