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護理雜誌 MEDLINEScopus

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篇名 癌症病人使用鴉片類藥物導致便秘之實證護理
卷期 57:4
並列篇名 Evidence-Based Nursing Care for Cancer Patients With Opioid-induced Constipation
作者 游千代柯乃熒
頁次 100-105
關鍵字 便秘癌症病人實證護理鴉片類藥物evidence-based nursingcancer patientsconstipationopioid drugsMEDLINEScopusTSCI
出刊日期 201008

中文摘要

約三分之一的癌症病人在使用鴉片藥物治療疼痛後出現便秘症狀,臨床醫療人員處理便秘的方式
常採取專家意見,缺乏實證的基礎,以至於癌症病人的便秘問題常常不能有效解決。本文以美國
2009年最新癌症緩和照護網路指引為基礎,並以實證護理研究文獻修改內容。當癌症病人使用鴉片藥物治療疼痛時,需先執行詳細的便秘評估,在病人尚未發生便秘之前,就需提供預防措施,藥物為Sennoside加上Docusate,非藥物則為運動、高纖維的飲食及腹部按摩預防便秘。如果已
發生便秘,一開始先使用Bisacodyl(Ducolax),如 果 仍 持 續 便 秘, 則 改 變 為Lactulose加 上Sennoside,在措施進行中,如果有糞便嵌塞的問題,先予指診再給予甘油灌腸。護理人員在癌症病人開始使用鴉片藥物之時,應建議醫師提早使用預防措施,每日評估病人便秘症狀及衛教病人採取非藥物的方法降低便秘症狀,進而提高癌症病人的生活品質。

英文摘要

About one-third of cancer patients who receive opioid drugs to control pain experience constipation. While clinical healthcare personnel often deal with constipation problems by adopting professional suggestions, effective evidence-based solutions remain lacking. Thus, cancer patient constipation prob-lems are often not effectively solved. In this article, 2009 American National Comprehensive Cancer Network guidelines for palliative care in cancer were modifed as the basis of evidence-based nurs-ing research. Constipation assessments should frst be conducted before the initiation of opioid drug treatment to relieve pain in cancer patients. Before the patient develops opioid-induced constipation, preventive action should be conducted, such as using drug combinations (e.g., sennoside and docusate). Non-pharmaceutical interventions include exercising, maintaining a high-fber diet, conducting ab-dominal massage and having correct bowel habits. If the patient is already experiencing constipation, bisacodyl (ducolax) may be used. However, if no improvement is observed, pharmaceutical treatments (e.g., a lactulose-sennoside combination) may be administered. If stool impaction occurs during the testing process, digital and glycerine should be implemented to remove stool impaction. Eliminating stool impaction enhances medication effectiveness. Nurses should advise doctors regarding preventive measures related to commencing treatment with opioid drugs. Further, nurses must evaluate degree of constipation and educate patients on following non-pharmaceutical strategies to alleviate constipation to improve quality of life.

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