文章詳目資料

Annals of Nuclear Medicine and Molecular Imaging

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篇名 Diagnosis and Monitoring Treatment Response of Skeletal Tuberculosis of Foot by Three-phase Bone Scan: A Case Report
卷期 23:3
並列篇名 三相骨骼掃描用於診斷骨結核及評估治療效果:病例報告
作者 蔡雅茹蕭聿謙
頁次 175-180
關鍵字 skeletal tuberculosisfootthree-phase bone scan骨結核三相骨骼掃描
出刊日期 201009

中文摘要

骨結核是一種罕見的疾病,約佔所有結核病皂的1-39毛。骨結核大部分侵犯脊椎,位於足部的骨結核並不常見。我們報告一個病例罹患左足的骨結核。利用三相骨路掃描診斷出左足的骨髓炎,進一步評估為骨結核感染。病患接受抗結核藥物的期間,三中目骨絡掃描顯示骨髓炎有部分緩解。一年後抗結核治療完成,以三相骨路掃描追蹤,檢查結果為正常。要成功治療骨結核必須早期診斷及早期抗結核治療。骨結核確定診斷需要骨俗切片與細菌培養。臨床上一些非侵犯性的檢查方法也是很有用的檢查工具。骨有各掃描對於診斷骨結核是敏感的檢查。對於疑似骨結核的病人,骨骨各掃描能早期診斷並評估全身的骨憾,必要時作為切片的依據。對於有骨髓炎症狀的人,當骨俗掃描有異常時,應該把骨結核放進鑑別診斷裡。另外,骨路掃描對於評估抗結核治療效果可能是有幫助的。

英文摘要

Skeletal tuberculosis (TB) is a very rare disease com-prising 1-3% of the total population of TB patients.Skeletal TB most often involves the spine. Involvement of foot is uncommon. We presented a case of skeletal TB of left foot. The initial three-phase bone scan showed a strongly positive result indicating osteomyelitis of left foot. Further evaluation confirmed the diagnosis of skeletal TB. Three-phase bone scan revealed partial resolution during anti-TB therapy. A negative study was shown one year later after clinical resolution of the disease. The successful treatment of skeletal TB requires early diagnosis and early anti-TB therapy. The definitive diagnosis of skeletal TB is isola-tion of bacteria from a bone biopsy. In clinical practice, noninvasive methods are useful diagnostic tools includ-ing clinical information, imaging studies, and laboratory findings. Three-phase bone scan is a sensitive test for diagnosis of skeletal TB. In cases of suspected skeletal TB, it can allow assessment of entire skeleton and pro-vide guidance for biopsy in early stage when radiologi-cal imaging is normal. In cases with symptoms of bone infection, tuberculosis should be considered in differen-tial diagnoses if bone scintigraphy is positive. Finally, three-phase bone scan might be helpful in monitoring treatment response of anti-TB therapy.

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