食道癌的早期診斷與治療技術的進步延長了食道癌病人的存活期；因此以胃作重建食道之續發性胃癌將成為癌症專家之特殊議題。我們發表一位食道癌病人接受食道切除術，並以胃作重建食道長期追蹤後發現第二個癌症在食道重建的胃內。外科切除是這種續發癌治療之首選；癌的早期診斷與內視鏡黏膜切除術是獲得良好預後的基本條件。放射線治療是對無法手術、拒絕接受手術或需要術後輔助治療的病人所應考慮的一種治療模式。

Early detection of esophageal cancer and advance in therapeutic techniques increase the survival of esophageal cancer patients; therefore, reconstructed gastric tube cancer may become a special issue for oncologists. We present a case of esophageal cancer after esophagectomy and gastric tube reconstruction with long-term remission who developed a second cancer in reconstructed gastric tube Surgical intervention is the first priority choice of treatment, and endoscopic mucosal resection (EMR) for early cancer might result in good prognosis. Radiotherapy should be considered for inoperable patients or as an adjuvant mode after surgery.