當病人因感染或全身系統性疾病導致冷凝球蛋白血症發生時，會改變正常生理功能，而面對此疾病的過程中，焦慮感常油然而生。本文針對一位年輕男性，於2007年5月25日至6月3日的護理期間，經Gordon功能性健康型態評估收集資料，發現個案在治療過程中因侵入性導管留置而使其潛在危險性感染之風險提高;因冷凝球蛋白血症導致腎絲球腎炎而引發體液容積過量;個案在患病和確立診斷的過程中承受拯大心理壓力，常出現焦慮的情形。在二迫的護理過程中筆者與個案和家屬建立良好的治療性護病關係，經由討論、教導等方式，在家屬及個案共同努力下，逐漸暸解此少見疾病的照護方法，進而減輕其焦慮，以積拯的態度對抗疾病，期望藉此成功案例提供給臨床照謹此類病人之護理人員參考。

Cryoglobulinemia occurs when patients suffered from the infection or systemic disease. The disease not only altered physiological function， but also induced anxiety. We cared a young man during the period between May 25 and June 3， 2007. We applied Gordon's functional health assessment index to evaluate the patient. Health problems identified included risk for infection by invasive catheter retention， fluid volume excess by cryoglobulinemia induced glomerular nephritis， and anxiety by intensive mental stress. During the nursing process of two weeks， we established trusting therapeutic relationship with the patient and his family. They were able to understand the caring intervention of the rare disease gradually through discussion and training. Finally， the patient relieved the anxiety and took an aggressive attitude to fight against the disease. We hope to share the caring experience with readers.