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臺灣應用輻射與同位素雜誌

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篇名 典型與流行性卡波西氏肉瘤放射治療
卷期 1:1
並列篇名 Radiotherapy for Classic Kaposi's Sarcoma and Epidemic Kaposi's Sarcoma
作者 黃國明成佳憲林文傑趙曉玲胡志忠黃文濤
頁次 035-041
關鍵字 典型性卡波西氏肉瘤流行性卡波西氏肉瘤放射治療反應率Classic Kaposi's sarcomaEpidemic Kaposi's SarcomaRadiotherapyResponse rate
出刊日期 200512

中文摘要

本篇研究在評估放射治療對於典型性與流行性卡波西氏肉瘤局部控制及症狀解除的效果,並探討放射治療技術的應用。本次研究收集在1993年l月至2005年4月間,共22例,於臺大醫院經病理切片證實爲卡波西氏肉瘤,且有接受放射治療者爲研究對象。其中典型性卡波西氏肉瘤,有10例共22個病灶;因罹患後天免疫性缺乏症候群併發的流行性卡波西氏肉瘤,則有12例共20個病灶。治療方式乃依據臨床症狀作選擇,並以水箱或填充物(bolus)輔助放射治療之效果。在典型卡波西氏肉瘤之22個病灶接受30-60格雷(平均36.8格雷),完全反應77.2 %,部分反應事22.8%。在罹患後天免疫性缺之症候群併發卡波西氏肉瘤之20個病灶接受8-40格雷(平均29.17格雷),完全反應率65%,部分反應率35%。由於放射治療技術及儀器材料的進步,局部放射治療對卡波西氏肉瘤是一種方便且有效的治療方式。

英文摘要

The purpose of this study is to evaluate the effects of local control and symptom relief of radiotherapy in treating classic and epidemic Kaposi's sarcoma (KS). The application of radiation therapy technique is also discussed. From January 1993 to April 2005, 20 patients with biopsy-proved KS and radiotherapy were enrolled in this study Among them, 10 cases with 22 lesions were classic KS. The other 12 cases with 20 lesions were epidemic KS caused by acquired immunodeficiency syndrome (AIDS). The design of radiotherapy was determined according to the clinical presentation individually. Water tank or tissue-equivalent bolus was used in some cases to facilitate the effect of radiotherapy. In patients with classic KS, 22 lesions were treated with 30 to 6OGy (average 36.8Gy). The complete response (CR) rate was 77.2% and partial response (PR) rate was 22.8%. In patients with AIDS-related KS, 20 lesions were treated with 8 to 4OGy (average 29.l7Gy). The CR rate was 65% and the PR rate was 35%. Due to the advancement of radiotherapy technique and material, radiotherapy is a convenient and effective treatment for KS.

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