對大多數左主幹冠狀動脈疾病的病人來說，冠狀動脈繞道手術和藥物治療是他們最常選擇的治療方式。而冠狀動脈繞道手術是個可信賴的治療方式，其術後存活時間可達十年以上；所以它比藥物治療有更多益處。隨著醫療器材的進步，傳統金屬支架的發明帶給這類病患嶄新的治療契機。經過十年多的發展，傳統金屬支架變得更易彎曲也更容易通過血管的狹窄部位。許多最新的研究顯示支架置放術對於左主幹冠狀動脈疾病的病人來說是個具有潛力的治療方式。本研究收集自1997年五月到2005年六月在本院接受左主幹冠狀動脈置放術的105位病患；每位病患都根據以下兩個標準進行篩選：一、因某些疾病無法接受冠狀動脈繞道手術的病患（癌症、腦中風、腎功能不全、肺功能不付佳和高齡）。二、病患本身拒絕冠狀動脈繞道手術。研究結果顯示女性和年紀輕的病患在接受左主幹冠狀動脈置放術後有較高的機會再進行冠狀動脈血管成形術或冠狀動脈繞道手術。此外，腦中風病史可預測因心血管致命的發生；較低的左心室射出比可預測整體死亡率。本研究的結論可以提供心臟科醫師和病患在選擇治療方式的重要參考。

Coronary artery bypass grafts (CABG) and medical treatment were used to be the choices for most patients with left main coronary artery (LMCA) disease. CABG was a relative credible treatment and the average survival period could extend more than ten years. CABG has been considered more beneficial compared to medical treatment. After many years of development in the area of medical devices, bare metal stents (BMS) were invented. The BMS becomes more flexible and easier to deliver to the narrowing part of the vessel. Many latest studies showed that stent implantation is a potential treatment for patients with LMCA disease. In this study, 105 patients was collected (78 men and 27 women, age 68�10 years) from May 1997 to June 2005 whom underwent stent implantation for LMCA disease in Shin Kong Wu Ho-So Memorial Hospital Each patient was selected according to two criteria: 1. Patient who can not accept operation because of other disease (cancer, stroke, renal dysfunction, lung dysfunction, and old age). 2. Patient refused CABS. The present study showed that female and young age groups show higher accuracy prediction of the repeated PCI and/or CABG after stunt implantation for LMCA disease. In addition, history of CVA could help predict the cardiovascular mortality and comparing lower LVEF could predict the total mortality. The conclusion will provide the interventional cardiologists and these patients as a valuable consultation for treatment.