膽囊腔內出血是一種少見的疾病。曾有些因膽囊炎、外傷、膽囊腫瘤、血友病或膽囊動脈瘤所引起的個案報告。而抗凝血劑的治療可能會因有出血傾向，以致造成一些併發症。不過因抗凝血劑治療而單獨產生膽囊腔內出血的併發症則很少被報導。我們報告一位因抗凝血劑治療而導致膽囊腔內出血的病例。這是一位八十歲的老先生因患有腦血管梗塞而服用抗血劑 - warfarin。他因為有慢性B型肝炎而接受腹部超音波及電腦斷層掃描檢查，意外發現膽囊有疑似腫瘤。他接受了腹腔鏡膽囊切除術，結果發現是單獨的膽囊腔內出血。我們推測這是因抗凝血劑治療而產生膽囊腔內出血的併發症。所以我們建議對於使用抗凝血劑治療的患者如果有不明的膽囊腫瘤時，必須把膽囊腔內出血列入鑑別診斷。

The gallbladder hemorrhage is a rare disease. Some reported cases were associated with cholecystitis,trauma, neoplasm, hemophilia or cystic artery aneurysm. Anticoagulation therapy caused some complications due to bleeding tendency. But gallbladder hemorrhage after anticoagulation therapy was rarely reported. We reported a case with gallbladder hemorrhage after anticoagulation therapy. This was an 80 year-old male patient who had anticoagulant - warfarin, for cerebral infarction. He was found to have a gallbladder tumor during routine abdominalultrasonography for chronic hepatitis B. He underwent laparoscopic cholecystectomy and intraluminal hemorrhage of gallbladder was discovered. We suggested
that the patient had gallbladder hemorrhage due to the complication of anticoagulation therapy. We concluded that gallbladder hemorrhage should be included in the differential diagnosis of patients with a gallbladder tumor.