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篇名 裘馨型肌肉失養症體脂肪分析
卷期 27:5
並列篇名 Body Fat Analysis of Patients with Duchenne Muscular Dystrophy
作者 呂怡靜林榮豊陳秋坪陳順勝
頁次 249-255
關鍵字 Body weightStatureBody fatBody mass indexDuchenne muscular dystrophy體重身高體脂肪身體質量指數裘馨型肌肉失養症TSCI
出刊日期 200209

中文摘要

背景與目的:裘馨型肌肉失養症病患肌肉會進行性萎縮無力,若又加上肥胖會使功能更差,並且增加照顧者負擔。本研究目的為測量裘馨型肌肉失養症病患之體態以及利用生物電子阻抗分析方法測量全身體脂肪含量,並與正常人比較其差異。研究方法:本研究分為兩個部分,第一部份測量使用生物電子阻抗分析儀測量裘馨型肌肉失養症全身體脂肪含量信度分析,包括施測者間信度分析與再測信度分析。第二部份正式研究裘馨型肌肉失養症病患體態與體脂肪含量並與年齡配對之正常人比較。病患及年齡配對的正常男性各33人,測量其身高、體重、身體質量指數和全身體脂肪含量。結果:以生物電子阻抗分析儀測量裘馨型肌肉失養症全身體脂肪含量不論是施測者間信度或再測信度均很高,ICC數值均為0.99。裘馨型肌肉失養症病患之身高與體重明顯低於正常男性,t值分別為-10.66和-4.41(p<0.001)。身體質量指數方面兩組之間並無顯著差異,t值為-0.89(p=0.38)。而體脂肪含量裘馨型肌肉失養症病患明顯高於正常男性,t值為10.40(p<0.001)。結論與建議:病患身高體重明顯不同於正常男性,身高較矮體重較輕,但是身體質量指數並無差異,而體脂肪含量病患的數值卻遠大於正常男性,因此身體質量指數的高低應用在裘馨型肌肉失養症無法視為體脂肪多寡的依據。

英文摘要

Background and purposes: Patients with Duchenne muscular dystrophy (DMD) suffer from progressive muscle weaknesses, which substantially influence their daily performances. In fact, the functional status of DMD patients can be made worse by the presence of obesity that may create a greater burden for caregivers. The purposes of this study were twofold: (1) to delineate the physical stature, body weight and body fat of DMD patients, and (2) to compare those differences between DMD patients and normal controls in Taiwan. Methods: The study design included two parts. In the first part, the inter-rater and test-retest reliabilities of the bioelectric impedance analysis of total fat in individuals with DMD were determined. As for the second part, a comparisons were performed in terms of the height, body weight, body mass index, as well as body fat between DMD patients and 33 age-matched, normal counterparts. Results: The inter-rater and the test-retest reliabilities of the bioelectric impedance analysis of total fat were high, with intraclass correlation coefficient values of 0.99, respectively. Significant between-group differences emerged in height and weight (t = -10.66, -4.41 respectively, p<0.001). The body mass index of DMD patients was not significantly different from that of normals (t = -0.89, p = 0.38), whereas DMD patients obtained higher body fat values than normal subjects (t = 10.40, p<0.00l). Conclusions: Relative to the normal controls, most of our DMD patients were shorter and lighter. The body mass index values of DMD patients were within normal limits, and that their total body fat values were much higher than those of normals. Therefore, the value of body mass index should not be regarded as the reference for the estimation of total body fat in patients with DMD.

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