前置清腸作業(bowel preparation)的徹底與否影響到接下來大腸鏡檢查的準確率。因此，選擇一個價錢合理的、效果不錯的而且病人接受度又高的清腸劑(bowel cleansing regimen)變得十分地重要。而目前各國普遍使用，受檢者接受度也比較高的，為口服磷酸鈉製劑（例如：Fleet Phospho-soda屬之）。然而有愈來愈多的案例報導指出，有些個案在使用Fleet Phospho-soda後發生嚴重的血中電解質異常或急性腎損傷的情形。嚴重的高血磷症以及低血鈣症一旦發生了，若沒有及時作適當處置，可能會因為腎鈣質沈積(nephrocalcinosis)導致急性磷酸鹽腎病變的形成，進一步惡化了腎臟功能。本文擬針對Fleet Phospho-soda所致之電解質變化與腎臟毒性等藥物不良反應做一文獻回顧探討。

Ideal bowel preparation improves diagnostic accuracy of colonoscopy. Thus, it is important to choose a non-expensive, effective, and well-tolerated bowel cleansing regimen. One of the most satisfying regimens is oral sodium phosphate, e.g. Fleet Phospho-soda. However, more and more case reports reveal that serious electrolyte disturbance (e.g. hyperphoshatemia, hypocalcemia) and acute kidney injury occur occasionally in those who ever used Fleet Phospho-soda. If we do not treat serious hyperphoshatemia and hypocalcemia in time, acute phosphate nephropathy will progress and then worsen kidney function. In this article, we made a literature review in these studies focus on electrolyte disturbance and kidney injury following oral Fleet Phospho-soda.