篇名 | Comparison of In-Hospital Outcome of Acute ST Elevation Myocardial Infarction in Patients with versus without Diabetes Mellitus |
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卷期 | 27:3 |
作者 | Hong-Pin Hsu 、 Yu-Lan Jou 、 Shing-Jong Lin 、 Min-Ji Charng 、 Ying-Hwu Chen 、 Wen-Shin Lee 、 Tse-Ming Lu 、 Lung-Ching Chen 、 Pai-Feng Hsu 、 Po Hsun Huang 、 Hsin-Bang Leu 、 Tao-Cheng Wu |
頁次 | 145-151 |
關鍵字 | Acute ST elevation myocardial infarction 、 Diabetes mellitus 、 Outcome 、 MEDLINE 、 SCI 、 Scopus |
出刊日期 | 201109 |
Background: Diabetes mellitus (DM) is a stronger risk factor for coronary artery disease (CAD) and is associated with mortality and morbidity of cardiovascular disease. The in-hospital outcome in diabetic patients with acute ST elevation myocardial infarction (STEMI) is less known. The aim of this study is to evaluate in-hospital outcome of acute STEMI in patients with diabetes mellitus.
Methods: The patients with acute STEMI between November 2007 to June 2009 were enrolled, the traditional risk factors for CAD, the inflammatory marker and coronary angiographic results were recorded. The in-hospital
outcome of patients with and without DM were compared.
Results: Total 239 patients with acute STEMI were enrolled. Of those, 94 (39%) were diabetic and 145 (61%) were non-diabetic patients. Older, multi-vessel diseases, poor renal function, higher killip class and the higher inflammatory marker level were associated with in-hospital mortality in patients with STEMI. In-hospital mortality was higher in diabetic than non-diabetic patients (23.4% vs. 7.6%, p = 0.001). Previous hypertension, cerebral vascular disease were more frequent in diabetic than in non-diabetic patients. Diabetic patients also demonstrated
higher creatinine level than non-diabetic patients (creatinine: 2.14 ± 1.54 vs. 1.34 ± 0.99 mg/dl, p < 0.001).
Conclusion: This study suggests that in diabetic patients with acute STEMI, in-hospital mortality rate is higher than in non-diabetic patients. The aggressive treatment early in the course of diabetic patients with acute STEMI is important.